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极低脂饮食能扭转六个月的2型糖尿病

发布时间:2017-09-06

A new study from Newcastle University finds that people with type 2 diabetes can reverse their condition for up to six months after eating a very low calorie diet(VLCD) for eight weeks.

纽卡斯尔大学一项新的研究发现,2型糖尿病患者采用极低脂饮食(VLCD)八周后,可以把病程逆转最多6个月。

极低脂饮食能扭转六个月的2型糖尿病

This is the latest research from Professor Roy Taylor, Newcastle University, who found in a 2011 study that type 2 diabetes can be reversed by eating 800 calories per day for eight weeks.

这项最新的研究来自纽卡斯尔大学的Roy Taylor教授,Roy Taylor教授在2011年的时候建立了该研究,研究表明每天摄入800卡路里坚持八周,可以扭转糖尿病。

Three months later, seven of the 11 participants were free of type 2 diabetes. But questions remained as to whether this reversal of type 2 diabetes – which occurred because weight loss led to fat removal from the pancreas, restoring insulin production to normal – can be achieved in the longer-term.

3个月后,11名受试者中的7人摆脱了糖尿病,但是,问题是,所谓的逆转2型糖尿病,即体重减轻而致的脂肪从胰腺转移出来,且胰岛素分泌维持正常,这种改善是否能在长期情况下中达到呢?

In this new study, Taylor’s team recruited 30 volunteers with type 2 diabetes. The diabetes duration of participants ranged between six months and 23 years. All oral medication and insulin was stopped before the study began.

在这项新的研究中,Taylor的团队招募了30名2型糖尿病志愿者。这些受试者的糖尿病病程为6个月到23年之间。在研究开始之后,所有的口服降糖药和胰岛素都停止使用。

The participants had the same diet of 600 to 700 calories a day for eight weeks. Glucose control, insulin sensitivity, insulin secretion and hepatic and pancreas fat were all monitored.

受试者使用相同的饮食,每天热量为600-700卡路里,为期八周。全程监测血糖控制、胰岛素敏感性、胰岛素分泌以及肝脏和胰腺的脂肪。

Overall, 12 patients who had type 2 diabetes for less than 10 years managed to reverse their condition. After six months, their insulin production remained normal and the condition remained reversed. At this stage, another 13th patient then reversed their type 2 diabetes.

总的来说,12名患2型糖尿病至少10年的患者参与管理逆转了自身的病程。6个月后,他们的胰岛素分泌保持在正常状态,且病程得到逆转。在这个阶段, 另外一名患者也逆转了其自身的2型糖尿病。

Taylor said: “What we have shown is that it is possible to reverse your diabetes, even if you have had the condition for a long time, up to around 10 years. If you have had the diagnosis for longer than that, then don’t give up hope – major improvement in blood sugar control is possible.”

Taylor说:“我们展示的研究成果是为了逆转糖尿病病程是有可能的,尽管你已经患病很长一段时间,长至大概10年。如果你已经确诊超过这个时间,也不要放弃希望——主要的血糖控制改善还是可能的。”

Participants lost an average of 14 kilograms (just over 2st) during the eight-week study, and after six months they did not regain any weight, which is crucial in ensuring that remission is achieved in the long-term. Patients who regain lost weight after following a VLCD can end up back on medication.

在研究的八周时间内,受试者平均减重14kg,并且在6个月后,受试者的体重没有反弹,这需要严格执行,以保证在长期时间内改善的成果有效。在执行VLCD后体重反弹的患者最终还是需要服用药物的。

“The study also answered the question that people often ask me – if I lose the weight and keep the weight off, will I stay free of diabetes? The simple answer is ‘yes’,” said Taylor.

Taylor说,“这项研究可以回答人们经常问我的问题了,如果我减重并保持体重不反弹,我是否可以摆脱糖尿病?答案是——是的”。

“Interestingly, even though all our volunteers remained obese or overweight, the fat did not drift back to clog up the pancreas. The bottom line is that if a person really wants to get rid of their type 2 diabetes, they can lose weight, keep it off and return to normal.

有趣的是,尽管我们的受试者依然是肥胖或者超重,但其脂肪没有转移至堵塞胰腺。最主要的是,如果患者本身真的希望摆脱2型糖尿病,他们可以坚持减重,并恢复到正常。

“This is good news for people who are very motivated to get rid of their diabetes. But it is too early to regard this as suitable for everyone. That is a separate question and a major study is underway to answer this.”

“这对于有意愿摆脱糖尿病的患者来说是一个好消息,但如果说这适合于每一个人的话,则为时太早,这是另外一个问题,需要另外的研究进行回答。”

The findings appear in the online journal Diabetes Care.
该研究发表于Diabetes Care的网上期刊